2-Chloro-3-methyl-5-nitropyridine → HCID 59336153, compound

HRID 2359522Notes

Reaction equation

HRID 2359522 reaction equation
Cl[C:2]1[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.[NH2:12][CH2:13][C:14]([N:16]([CH:18]1[CH2:23][CH2:22][N:21]([CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:20][CH2:19]1)[CH3:17])=[O:15]>>[CH2:24]([N:21]1[CH2:20][CH2:19][CH:18]([N:16]([CH3:17])[C:14](=[O:15])[CH2:13][NH:12][C:2]2[C:7]([CH3:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=2)[CH2:23][CH2:22]1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 896482-Chloro-3-methyl-5-nitropyridineHCID 66565199HCID 66565199, compound

Product 1

HCID 59336153HCID 59336153, compound

Procedure

The title compound was synthesized from 2-chloro-3-methyl-5-nitropyridine and 2-amino-N-(1-benzylpiperidine-4-yl)-N-methylacetamide in the same manner as in Example 10.

Sources & evidence

ORD record
ord-9f7d4af6d7454ce9a1335bc3e5223e30
Source dataset
uspto-grants-2014_04
Patent number
US08685989B2

Reaction notes

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