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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2359523Generated: October 26, 2026

2-[(5-Chloropyridin-3-yl)oxy]acetic acid → 2-(5-chloropyridine-3-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylacetamide hydrochloride

https://huagongshe.com/reaction/2359523

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(5-Chloropyridin-3-yl)oxy]acetic acidHCID 22265974—
Reactant1-(cyclopropylmethyl)-N-methylpiperidine-4-amineHCID 43314908—
Product2-(5-chloropyridine-3-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylacetamide hydrochlorideHCID 68412547—

Reaction Steps

The title compound was synthesized from 2-(5-chloropyridine-3-yloxy)acetic acid and 1-(cyclopropylmethyl)-N-methylpiperidine-4-amine in the same manner as in Example 95.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08685989B2
Source datasetuspto-grants-2014_04
ORD IDord-0d6ee27a51fd40629bd86df2ebfc9dbb
Source noteuspto-grants-2014_04