Chloroform → HCID 178515902, compound

HRID 235955Notes

Reaction equation

C[C:2]1[CH:3]=[C:4]([C:10]2[NH:11][CH:12]=[C:13]([C:15]3[S:16][CH:17]=[CH:18][CH:19]=3)[N:14]=2)[CH:5]=[CH:6][C:7]=1[O:8]C.C(Cl)(Cl)[Cl:21]>>[Cl:21][C:2]1[CH:3]=[C:4]([C:10]2[NH:11][CH:12]=[C:13]([C:15]3[S:16][CH:17]=[CH:18][CH:19]=3)[N:14]=2)[CH:5]=[CH:6][C:7]=1[OH:8]

Participants

Reactant 2

HCID 6212Chloroform

HCID 178488931HCID 178488931, compound

Product 1

HCID 178515902HCID 178515902, compoundYield 86%

Procedure

Compound 29 was prepared as described for 24 except that 28 was used in place of 23; 86% yield; m.p. 152°-3° C. (CHCl3).

Sources & evidence

ORD record: ord-5fe52bc2d6c14726a67b4cc11ffb4213
Source dataset: uspto-grants-1987_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04642311

Reaction notes

Loading…