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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2359571Generated: November 1, 2026

2-Aminopyridine → HCID 58315408, compound

https://huagongshe.com/reaction/2359571

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminopyridineHCID 10439—
Reactant2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamideHCID 58315432—
ProductHCID 58315408HCID 58315408293.8%

Reaction Steps

Following Buchwald Method B, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (100 mg, 0.34 mmol) and pyridine-2-ylamine (64 mg, 0.68 mmol) gave 7-cyclopentyl-2-(pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (350 mg, 84%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08685980B2
Source datasetuspto-grants-2014_04
ORD IDord-4b0ed471525d4e389d997876c07aead8
Source noteuspto-grants-2014_04