HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentane, 1-bromo-4-methyl- → HCID 58315400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentane, 1-bromo-4-methyl- | HCID 69385 | — |
| Reactant | Ribociclib | HCID 44631912 | — |
| Product | HCID 58315400 | HCID 58315400 | 42% |
Reaction Steps
Following General Procedure D, 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (100 mg, 0.230 mmol) and 1-bromo-4-methyl pentane (103 mg, 0.690 mmol) gave 7-cyclopentyl-2-{5-[4-(4-methyl-pentyl)-piperazin-1-yl]-pyridin-2-ylamino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (50 mg, 42%). MS (ESI) m/z 519.4 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08685980B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-d65b4f7f65e247189568780f1bd51772 |
| Source note | uspto-grants-2014_04 |