HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11232035, compound → HCID 44819127, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11232035 | HCID 11232035 | — |
| Reactant | 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide | HCID 58315432 | — |
| Product | HCID 44819127 | HCID 44819127 | 28.8% |
Reaction Steps
Following Buchwald Method B, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (50 mg, 0.17 mmol) and 4-(6-amino-pyridin-3-yl)-2,2-dimethyl-piperazine-1-carboxylic acid tert-butyl ester (58 mg, 0.15 mmol) gave 7-cyclopentyl-2-[5-(3,3-dimethyl-piperazin-1-yl)-pyridin-2-ylamino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (20 mg, 25%). MS (ESI) m/z 463.3 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08685980B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-3ff5928856ce42d6ae5d20a0ff524b64 |
| Source note | uspto-grants-2014_04 |