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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2359844Generated: November 1, 2026

1,4-Dioxane → HCID 16045868, compound

https://huagongshe.com/reaction/2359844

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
Reactant2-Amino-5-chlorobenzaldehydeHCID 2773898—
ReactantHCID 21850027HCID 21850027—
Solventtert-ButanolHCID 6386—
ProductHCID 16045868HCID 16045868—

Reaction Steps

The title compound was synthesized according to EXAMPLE 11 from 2-amino-5-chlorobenzaldehyde and 3-(2,6-dimethoxyphenyl)propionitrile. Instead of dioxane, tert-butanol was used from [sic; as]1 the solvent. 1TN: “aus” (from) appears to be a typo for “als” (as).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686002B2
Source datasetuspto-grants-2014_04
ORD IDord-e32dd35d1f9b47779c71041fe6378791
Source noteuspto-grants-2014_04