6-Amino-2H-1,3-benzodioxole-5-carbaldehyde → HCID 68551205, compound
Reaction equation
[NH2:1][C:2]1[C:3]([CH:11]=O)=[CH:4][C:5]2[O:9][CH2:8][O:7][C:6]=2[CH:10]=1.[F:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[C:15]=1[CH2:22][CH2:23][C:24]#[N:25]>>[F:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[C:15]=1[CH2:22][C:23]1[C:24]([NH2:25])=[N:1][C:2]2[CH:10]=[C:6]3[O:7][CH2:8][O:9][C:5]3=[CH:4][C:3]=2[CH:11]=1Participants
3
Procedure
The title compound was synthesized according to EXAMPLE 11 from 6-amino-1,3-benzodioxole 5-carbaldehyde and 3-(2-fluoro-6-methoxyphenyl)propionitrile.
Sources & evidence
- ORD record
- ord-952dd1f87fe441a5a092c471877b44e4
- Source dataset
- uspto-grants-2014_04
- Patent number
- US08686002B2
Reaction notes
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