2-Amino-5-fluorobenzaldehyde → HCID 68546270, compound

HRID 2359854Notes

Reaction equation

HRID 2359854 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([F:10])=[CH:6][C:3]=1[CH:4]=O.[F:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[C:13]=1[CH2:20][CH2:21][C:22]#[N:23]>>[F:10][C:7]1[CH:6]=[C:3]2[C:2](=[CH:9][CH:8]=1)[N:1]=[C:22]([NH2:23])[C:21]([CH2:20][C:13]1[C:14]([O:18][CH3:19])=[CH:15][CH:16]=[CH:17][C:12]=1[F:11])=[CH:4]2

Participants

3

Reactant 2

HCID 157407552-Amino-5-fluorobenzaldehydeHCID 68550217HCID 68550217, compound

Product 1

HCID 68546270HCID 68546270, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 2-amino-5-fluorobenzaldehyde and 3-(2-fluoro-6-methoxyphenyl)propionitrile. Reaction temperature 100° C.

Workup

  1. customReaction temperature 100° C.

Sources & evidence

ORD record
ord-4e8c638fa08f40d8b733aba196486da7
Source dataset
uspto-grants-2014_04
Patent number
US08686002B2

Reaction notes

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