4-Aminonicotinaldehyde → HCID 68550597, compound

HRID 2359864Notes

Reaction equation

HRID 2359864 reaction equation
[NH2:1][C:2]1[C:7]([CH:8]=O)=[CH:6][N:5]=[CH:4][CH:3]=1.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([F:18])[C:13]=1[CH2:19][CH2:20][C:21]#[N:22]>>[F:18][C:14]1[CH:15]=[CH:16][CH:17]=[C:12]([O:11][CH3:10])[C:13]=1[CH2:19][C:20]1[C:21]([NH2:22])=[N:1][C:2]2[C:7]([CH:8]=1)=[CH:6][N:5]=[CH:4][CH:3]=2

Participants

3

Reactant 2

HCID 27610334-AminonicotinaldehydeHCID 68550217HCID 68550217, compound

Product 1

HCID 68550597HCID 68550597, compound

Procedure

The title compound was synthesized according to EXAMPLE 11 from 4-aminonicotinaldehyde and 3-(2-methoxy-6-fluorophenyl)propionitrile.

Sources & evidence

ORD record
ord-ed67b14c30ea4eebaa9af6a77910dbc4
Source dataset
uspto-grants-2014_04
Patent number
US08686002B2

Reaction notes

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