HCID 18349590, compound → HCID 68554635, compound
Reaction equation
[NH2:1][C:2]1[CH:9]=[C:8]([F:10])[C:7]([F:11])=[CH:6][C:3]=1[CH:4]=O.[CH3:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH2:20][CH2:21][C:22]#[N:23]>>[F:11][C:7]1[CH:6]=[C:3]2[C:2](=[CH:9][C:8]=1[F:10])[N:1]=[C:22]([NH2:23])[C:21]([CH2:20][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[O:13][CH3:12])=[CH:4]2Participants
3
Procedure
The title compound was synthesized according to EXAMPLE 11 from 2-amino-4,5-difluorobenzaldehyde and 3-(2-methoxyphenyl)propionitrile.
Sources & evidence
- ORD record
- ord-6598bcf8a9de4e748cb24c774fbfcc4e
- Source dataset
- uspto-grants-2014_04
- Patent number
- US08686002B2
Reaction notes
Loading…