HCID 68550217, compound → HCID 68554012, compound
Reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[CH:6][C:3]=1[CH:4]=O.[CH3:16][O:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[C:19]=1[CH2:25][CH2:26][C:27]#[N:28]>>[CH3:16][O:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[C:19]=1[CH2:25][C:26]1[C:27]([NH2:28])=[N:1][C:2]2[C:3]([CH:4]=1)=[CH:6][C:7]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[CH:8][CH:9]=2Participants
3
Procedure
The title compound was synthesized according to EXAMPLE 11 from 2-amino-5-morpholin-4-ylbenzaldehyde and 3-(2-methoxy-6-fluorophenyl)propionitrile.
Sources & evidence
- ORD record
- ord-9ecbcc514a2b4e18a90e8816dd1e169e
- Source dataset
- uspto-grants-2014_04
- Patent number
- US08686002B2
Reaction notes
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