Sodium borohydride → HCID 20217711, compound

HRID 236006Notes

Reaction equation

HRID 236006 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[N:9][C:10]2[N:11]([CH2:20][CH:21]([CH3:23])[CH3:22])[C:12]3[N:13]([CH2:17][CH2:18][N:19]=3)[C:14](=[O:16])[CH:15]=2)=[CH:4][CH:3]=1.[BH4-].[Na+]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:10]2[N:11]([CH2:20][CH:21]([CH3:23])[CH3:22])[C:12]3[N:13]([CH2:17][CH2:18][N:19]=3)[C:14](=[O:16])[CH:15]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 54551056HCID 54551056, compound

Product 1

HCID 20217711HCID 20217711, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of the product of Procedure 85 (0.15 mol) and sodium borohydride (0.16 mol) in 250 ml. ethanol is stirred and refluxed for 4 hrs., then concentrated in vacuo. The residue is purified by recrystallization.

Workup

  1. temperaturerefluxed for 4 hrs
  2. concentration, then concentrated in vacuo
  3. customThe residue is purified by recrystallization

Sources & evidence

ORD record
ord-dcd040a4c0554664aa5298a6014533bc
Source dataset
uspto-grants-1987_02
Patent number
US04642345

Reaction notes

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