HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Tartaric acid → HCID 86658827, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Tartaric acid | HCID 444305 | — |
| Reactant | Sunitinib | HCID 5329102 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86658827 | HCID 86658827 | 92.3% |
Reaction Steps
Sunitinib (1.41 g, 3.53 mmol) was dissolved in boiling ethanol (130 ml), to which a solution of L-tartaric acid (0.53 g in 10 ml ethanol) was added and left to cool to room temperature to give 1.78 g of sunitinib L-tartarate. Melting point: 202-205° C. (Form I), ratio sunitinib/tartaric acid (according to NMR) 1:1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686023B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-540903a3e01647dd82a5df28590b0455 |
| Source note | uspto-grants-2014_04 |