Formic Acid → HCID 20217710, compound

HRID 236008Notes

Reaction equation

HRID 236008 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:10]2[N:11]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:12]3[N:13]([CH2:19][CH2:20][N:21]=3)[C:14](=[O:18])[C:15]=2[N:16]=O)=[CH:4][CH:3]=1.S(S([O-])=O)([O-])=O.[Na+].[Na+].[CH:34](O)=[O:35]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:10]2[N:11]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:12]3[N:13]([CH2:19][CH2:20][N:21]=3)[C:14](=[O:18])[C:15]=2[NH:16][CH:34]=[O:35])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 284Formic AcidHCID 24489Sodium DithioniteHCID 178448427HCID 178448427, compound

Product 1

HCID 20217710HCID 20217710, compound

Procedure

To a stirred solution of the nitroso compound of Procedure 87 (0.1 mol) in 200 ml. formic acid, sodium dithionite (0.25 mol) is added portionwise. After one hour, the reaction mixture is concentrated in vacuo, the residue dissolved in water and filtered. The filtrate is made basic with concentrated aqueous ammonia, and the product collected.

Workup

  1. concentrationthe reaction mixture is concentrated in vacuo
  2. dissolutionthe residue dissolved in water
  3. filtrationfiltered
  4. customthe product collected

Sources & evidence

ORD record
ord-f1c36abd6f434aa5870a30fe26e1c8fe
Source dataset
uspto-grants-1987_02
Patent number
US04642345

Reaction notes

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