1-Isocyanato-3-phenoxybenzene → 1-Benzylindolin-5-yl 3-phenoxyphenylcarbamate

HRID 2360124Notes

Reaction equation

HRID 2360124 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:18]([C:25]1[CH:26]=[C:27]([N:31]=[C:32]=[O:33])[CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[O:18]([C:25]1[CH:26]=[C:27]([NH:31][C:32](=[O:33])[O:17][C:13]2[CH:12]=[C:11]3[C:16](=[CH:15][CH:14]=2)[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:9][CH2:10]3)[CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 34456731-Isocyanato-3-phenoxybenzeneHCID 866598571-Benzylindolin-5-ol

Product 1

HCID 866598601-Benzylindolin-5-yl 3-phenoxyphenylcarbamate

Procedure

The title compound was synthesized from 1-benzylindolin-5-ol (30.0 mg, 0.133 mmol) using the same procedure employed for Example 2 (2), but with 3-phenoxyphenylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained having the following characteristics (16.5 mg, 28%).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-b07bc237f2c74a70a0fe322c7a51288b
Source dataset
uspto-grants-2014_04
Patent number
US08686024B2

Reaction notes

Loading…