5-Isocyanato-1,3-dioxaindane → 1-Benzylindolin-5-yl 5-benzo[d][1,3]dioxolylcarbamate

HRID 2360126Notes

Reaction equation

HRID 2360126 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:18]1[O:26][C:25]2[CH:24]=[CH:23][C:22]([N:27]=[C:28]=[O:29])=[CH:21][C:20]=2[O:19]1>>[O:26]1[C:25]2[CH:24]=[CH:23][C:22]([NH:27][C:28](=[O:29])[O:17][C:13]3[CH:12]=[C:11]4[C:16](=[CH:15][CH:14]=3)[N:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH2:9][CH2:10]4)=[CH:21][C:20]=2[O:19][CH2:18]1

Participants

3

Reactant 2

HCID 52232135-Isocyanato-1,3-dioxaindaneHCID 866598571-Benzylindolin-5-ol

Product 1

HCID 468661441-Benzylindolin-5-yl 5-benzo[d][1,3]dioxolylcarbamate

Procedure

The title compound was synthesized from 1-benzylindolin-5-ol (35.0 mg, 0.155 mmol) using the same procedure employed for Example 2 (2), but with 3,4-(methylenedioxy)phenylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (21.6 mg, 34%) having the following characteristics.

Sources & evidence

ORD record
ord-6af1f3e9bb984fb2a18f1b3e47fff14d
Source dataset
uspto-grants-2014_04
Patent number
US08686024B2

Reaction notes

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