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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360128Generated: October 30, 2026

5-Isocyanato-2,3-dihydro-1-benzofuran → 1-Benzylindolin-5-yl 2,3-dihydro-1-benzofuran-5-ylcarbamate

https://huagongshe.com/reaction/2360128

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Isocyanato-2,3-dihydro-1-benzofuranHCID 2776156—
Reactant1-Benzylindolin-5-olHCID 86659857—
Product1-Benzylindolin-5-yl 2,3-dihydro-1-benzofuran-5-ylcarbamateHCID 86659862—

Reaction Steps

The title compound was synthesized from 1-benzylindolin-5-ol (35.0 mg, 0.155 mmol) using the same procedure employed for Example 2 (2), but with 2,3-dihydro-1-benzofuran-5-ylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (9.0 mg, 13%) having the following characteristics.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686024B2
Source datasetuspto-grants-2014_04
ORD IDord-10a3580c39b043c3906d22a2d4892ccf
Source noteuspto-grants-2014_04