Phenethyl isocyanate → HCID 46866146, compound

HRID 2360130Notes

Reaction equation

HRID 2360130 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:18]([N:26]=[C:27]=[O:28])[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:18]([NH:26][C:27](=[O:28])[O:17][C:13]1[CH:12]=[C:11]2[C:16](=[CH:15][CH:14]=1)[N:8]([CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[CH2:9][CH2:10]2)[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 160602Phenethyl isocyanateHCID 866598571-Benzylindolin-5-ol

Product 1

HCID 46866146HCID 46866146, compound

Procedure

The title compound was synthesized from 1-benzylindolin-5-ol (35.0 mg, 0.155 mmol) using the same procedure employed for Example 2 (2), but with phenethylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (22.0 mg, 38%) having the following characteristics.

Sources & evidence

ORD record
ord-62156d92f9944083a0de969538f3b44c
Source dataset
uspto-grants-2014_04
Patent number
US08686024B2

Reaction notes

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