Ethyl isocyanate → HCID 46866454, compound

HRID 2360140Notes

Reaction equation

HRID 2360140 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:18]([N:20]=[C:21]=[O:22])[CH3:19]>>[CH2:18]([NH:20][C:21](=[O:22])[O:17][C:13]1[CH:12]=[C:11]2[C:16](=[CH:15][CH:14]=1)[N:8]([CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[CH2:9][CH2:10]2)[CH3:19]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 866598571-Benzylindolin-5-ol

Product 1

HCID 46866454HCID 46866454, compound

Procedure

The title compound was synthesized from 1-benzylindolin-5-ol (15.0 mg, 66.6 μmol) using the same procedure employed for Example 2 (2), but with ethylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained having the following characteristics (12.4 mg, 63%).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-a8e375d5ef304ac9896c448290f1ad48
Source dataset
uspto-grants-2014_04
Patent number
US08686024B2

Reaction notes

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