5-Indanyl isocyanate → HCID 86659869, compound

HRID 2360141Notes

Reaction equation

HRID 2360141 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:18]1[C:26]2[C:21](=[CH:22][C:23]([N:27]=[C:28]=[O:29])=[CH:24][CH:25]=2)[CH2:20][CH2:19]1>>[CH2:18]1[C:26]2[C:21](=[CH:22][C:23]([NH:27][C:28](=[O:29])[O:17][C:13]3[CH:12]=[C:11]4[C:16](=[CH:15][CH:14]=3)[N:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH2:9][CH2:10]4)=[CH:24][CH:25]=2)[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 50036815-Indanyl isocyanateHCID 866598571-Benzylindolin-5-ol

Product 1

HCID 86659869HCID 86659869, compound

Procedure

The title compound was synthesized from 1-benzylindolin-5-ol (15.0 mg, 66.6 μmol) using the same procedure employed for Example 2 (2), but with 5-indanylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a solid (14.3 mg, 75%) having the following characteristics.

Sources & evidence

ORD record
ord-edb92bb7d7144306a2a4c69e224c40ab
Source dataset
uspto-grants-2014_04
Patent number
US08686024B2

Reaction notes

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