Phenyl isocyanate → HCID 86659872, compound

HRID 2360144Notes

Reaction equation

HRID 2360144 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18]1([N:24]=[C:25]=[O:26])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:18]1([NH:24][C:25](=[O:26])[O:17][C:13]2[CH:12]=[C:11]3[C:16](=[CH:15][CH:14]=2)[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:9][CH2:10]3)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 866598571-Benzylindolin-5-ol

Product 1

HCID 86659872HCID 86659872, compound

Procedure

The title compound was synthesized from 1-benzylindolin-5-ol (15.0 mg, 66.6 μmol) using the same procedure employed for Example 2 (2), but with phenylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (7.3 mg, 32%) having the following characteristics.

Sources & evidence

ORD record
ord-88ebcb45fbb34b4a96ad90fe554d2f8a
Source dataset
uspto-grants-2014_04
Patent number
US08686024B2

Reaction notes

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