Ethyl 1-bromocyclobutanecarboxylate → HCID 178517928, compound

HRID 2360239Notes

Reaction equation

HRID 2360239 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([NH:12][C:13]([NH2:15])=[S:14])[CH2:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.Br[C:17]1([C:21](OCC)=[O:22])[CH2:20][CH2:19][CH2:18]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([NH:12][C:13]3[S:14][C:17]4([C:21](=[O:22])[N:15]=3)[CH2:20][CH2:19][CH2:18]4)[CH2:9][CH2:10][CH2:11]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 97595Ethyl 1-bromocyclobutanecarboxylateHCID 86606006N-[1-(4-chlorophenyl)cyclobutyl]thiourea

Product 1

HCID 178517928HCID 178517928, compound

Procedure

Synthesis was performed from N-[1-(4-chlorophenyl)cyclobutyl]thiourea and ethyl 1-bromocyclobutanecarboxylate according to Method D.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-cdf7d5f3d1e842f287cc22568badbeae
Source dataset
uspto-grants-2014_04
Patent number
US08686011B2

Reaction notes

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