2,2,2-Trichloroethyl chloroformate → HCID 86656687, compound

HRID 2360378Notes

Reaction equation

HRID 2360378 reaction equation
[F:1][C:2]1[C:34]([NH:35][CH3:36])=[CH:33][CH:32]=[CH:31][C:3]=1[C:4]([NH:6][C:7]1[C:12]([C:13]([F:16])([F:15])[F:14])=[CH:11][C:10]([C:17]([F:29])([C:22]([F:28])([F:27])[C:23]([F:26])([F:25])[F:24])[C:18]([F:21])([F:20])[F:19])=[CH:9][C:8]=1[I:30])=[O:5].[Cl:37][C:38]([Cl:45])([Cl:44])[CH2:39][O:40][C:41](Cl)=[O:42]>>[F:1][C:2]1[C:3]([C:4](=[O:5])[NH:6][C:7]2[C:12]([C:13]([F:16])([F:15])[F:14])=[CH:11][C:10]([C:17]([F:29])([C:22]([F:27])([F:28])[C:23]([F:24])([F:25])[F:26])[C:18]([F:20])([F:21])[F:19])=[CH:9][C:8]=2[I:30])=[CH:31][CH:32]=[CH:33][C:34]=1[N:35]([CH3:36])[C:41](=[O:42])[O:40][CH2:39][C:38]([Cl:45])([Cl:44])[Cl:37]

Participants

3

Reactant 2

HCID 870632,2,2-Trichloroethyl chloroformateHCID 86656688HCID 86656688, compound

Product 1

HCID 86656687HCID 86656687, compound

Procedure

According to the method of 1-7 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide and 2,2,2-trichloroethoxycarbonylchloride.

Sources & evidence

ORD record
ord-c584a4f2ced746fe99d83da2834b0016
Source dataset
uspto-grants-2014_04
Patent number
US08686044B2

Reaction notes

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