2-Chloronicotinoyl chloride → HCID 86656690, compound

HRID 2360385Notes

Reaction equation

HRID 2360385 reaction equation
[NH2:1][C:2]1[C:3]([F:33])=[C:4]([CH:30]=[CH:31][CH:32]=1)[C:5]([NH:7][C:8]1[C:13]([O:14][C:15]([F:18])([F:17])[F:16])=[CH:12][C:11]([C:19]([F:28])([C:24]([F:27])([F:26])[F:25])[C:20]([F:23])([F:22])[F:21])=[CH:10][C:9]=1[Br:29])=[O:6].[Cl:34][C:35]1[N:43]=[CH:42][CH:41]=[CH:40][C:36]=1[C:37](Cl)=[O:38]>>[Br:29][C:9]1[CH:10]=[C:11]([C:19]([F:28])([C:20]([F:21])([F:22])[F:23])[C:24]([F:25])([F:26])[F:27])[CH:12]=[C:13]([O:14][C:15]([F:17])([F:18])[F:16])[C:8]=1[NH:7][C:5]([C:4]1[C:3]([F:33])=[C:2]([NH:1][C:37](=[O:38])[C:36]2[CH:40]=[CH:41][CH:42]=[N:43][C:35]=2[Cl:34])[CH:32]=[CH:31][CH:30]=1)=[O:6]

Participants

3

Reactant 2

HCID 27745412-Chloronicotinoyl chlorideHCID 86656691HCID 86656691, compound

Product 1

HCID 86656690HCID 86656690, compound

Procedure

According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluorobenzamide and 2-chloronicotinoylchloride.

Sources & evidence

ORD record
ord-ed8948e9f4964515ad2c41ca4abd2c66
Source dataset
uspto-grants-2014_04
Patent number
US08686044B2

Reaction notes

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