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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360407Generated: November 1, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997430, compound

https://huagongshe.com/reaction/2360407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant3-Benzyloxy-phenylboronic acidHCID 2734313—
ProductHCID 66997430HCID 6699743032.8%

Reaction Steps

The title compound (0.143 g) was prepared from 2,6-difluoro-4-bromo aniline (0.3 g, 1.4 mmol) and 3-(benzyloxy)phenylboronic acid (0.426 g, 1.8 mmol) as a colourless liquid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.49-7.44 (m, 2H), 7.39 (t, J 7.2, 2H), 7.35-7.26 (m, 4H), 7.24 (s, 1H), 7.18 (d, J 7.8, 1H), 6.91 (dd, J 1.9, 8.0, 1H), 5.33 (s, 2H), 5.16 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-7572ab3c16264f509edd399ee76772b6
Source noteuspto-grants-2014_04