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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360414Generated: October 31, 2026

4-Bromo-2-(trifluoromethoxy)aniline → HCID 46314437, compound

https://huagongshe.com/reaction/2360414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-(trifluoromethoxy)anilineHCID 737382—
Reactant2-Fluorophenylboronic acidHCID 2734354—
ProductHCID 46314437HCID 4631443757.1%

Reaction Steps

The title compound (0.294 g) was prepared from 2-trifluoromethoxy-4-bromo aniline (0.5 g, 1.9 mmol) and 2-fluorophenylboronic acid (0.345 g, 2.5 mmol) as a yellow liquid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.47 (td, J 1.2, 4.7, 1H), 7.33-7.20 (m, 5H), 6.89 (d, J 8.8, 1H), 5.62 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-cffc5190ab8249b68f218eaaef8a22fe
Source noteuspto-grants-2014_04