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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360416Generated: October 31, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997347, compound

https://huagongshe.com/reaction/2360416

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant3-Isopropoxybenzeneboronic acidHCID 5083932—
ProductHCID 66997347HCID 6699734753.8%

Reaction Steps

The title compound (0.34 g) was prepared from 4-Bromo-2,6-difluoro aniline (0.5 g, 2.4 mmol) and 3-isopropoxyphenylboronic acid (0.337 g, 3.1 mmol) as a red liquid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.30-7.22 (m, 3H), 7.16-7.07 (m, 2H), 6.89 (dd, J 2.3, 8.1, 1H), 5.32 (s, 2H), 4.68 (septet, J 6, 1H), 1.26 (d, J 6, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-798cd94d750a43d2ad7db93f386c0178
Source noteuspto-grants-2014_04