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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360421Generated: October 28, 2026

4-Bromo-2,6-difluoroaniline → HCID 46314357, compound

https://huagongshe.com/reaction/2360421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant2-Fluorophenylboronic acidHCID 2734354—
ProductHCID 46314357HCID 4631435791.8%

Reaction Steps

The title compound (0.492 g) was prepared from 4-bromo-2,6-difluoroaniline (0.5 g, 2.4 mmol) and 2-fluorophenylboronic acid (0.436 g, 3.12 mmol) as a yellow liquid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.51 (td, J 1.5, 7.9, 1H), 7.38-7.31 (m, 1H), 7.29-721 (m, 2H), 7.14 (d, J 8.6, 2H), 5.44 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-2f48a1da6974463d9e9455a74e6652f9
Source noteuspto-grants-2014_04