HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2,6-difluoroaniline → 3,5-Difluoro-3'-isobutoxybiphenyl-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2,6-difluoroaniline | HCID 610191 | — |
| Reactant | B-[3-(2-Methylpropoxy)phenyl]boronic acid | HCID 16217826 | — |
| Product | 3,5-Difluoro-3'-isobutoxybiphenyl-4-amine | HCID 66997696 | 60.1% |
Reaction Steps
The title compound (0.16 g) was prepared from 4-bromo-2,6-difluoroaniline (0.2 g, 0.96 mmol) and 3-isobutoxyphenylboronic acid (0.242 g, 1.2 mmol) as a yellow liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686048B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-1627c2ecbde74d788f3dd4bf0883f2a8 |
| Source note | uspto-grants-2014_04 |