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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360429Generated: October 31, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997746, compound

https://huagongshe.com/reaction/2360429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant(3-Fluoro-5-methoxyphenyl)boronic acidHCID 2763243—
ProductHCID 66997746HCID 6699774642%

Reaction Steps

The title compound (51 mg) was prepared from 4-bromo-2,6-difluoroaniline (100 mg, 0.48 mmol) and 3-fluoro-5-methoxyphenylboronic acid (106 mg, 0.62 mmol) as a yellow solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.35 (dd, J 2.1, 8.1, 2H), 7.06 (d, J10.2, 1H), 7.01 (s, 1H), 6.71 (dd, J 2, 8.8, 1H), 5.42 (s, 2H), 3.81 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-62c056afd6714961aad05a52adb6b815
Source noteuspto-grants-2014_04