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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360430Generated: October 28, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997729, compound

https://huagongshe.com/reaction/2360430

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant(2H-1,3-benzodioxol-5-yl)boronic acidHCID 2734371—
ProductHCID 66997729HCID 6699772959.8%

Reaction Steps

The title compound (143 mg) was prepared from 4-bromo-2,6-difluoroaniline (200 mg, 0.96 mmol) and benzo[d][1,3]dioxol-5-ylboronic acid (207 mg, 1.25 mmol) as a white solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.23-7.18 (m, 3H), 7.08 (dd, J 1.8, 8.2, 1H), 6.91 (d, J 8.1, 1H), 6.01 (s, 2H), 5.24 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-3a2d5dfdf7bb40728b3764d529f24314
Source noteuspto-grants-2014_04