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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360433Generated: October 30, 2026

(3-Fluoro-5-methoxyphenyl)boronic acid → HCID 66997519, compound

https://huagongshe.com/reaction/2360433

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Fluoro-5-methoxyphenyl)boronic acidHCID 2763243—
Reactant4-Bromo-2-chloro-6-fluoroanilineHCID 20434620—
ProductHCID 66997519HCID 6699751959.8%

Reaction Steps

The title compound (71 mg) was prepared from 4-bromo-2-chloro-6-fluoroaniline (100 mg, 0.44 mmol) and 3-fluoro-5-methoxyphenylboronic acid (97 mg, 0.57 mmol) as a pale-yellow solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.51-7.45 (m, 2H), 7.05 (d, J 10.3, 1H), 7.00 (s, 1H), 6.73 (dd, J 2.1, 4.2, 1H), 5.60 (s, 2H), 3.81 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-221d167cfe8e452f88e53d062b22a276
Source noteuspto-grants-2014_04