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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360435Generated: October 30, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997753, compound

https://huagongshe.com/reaction/2360435

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant(2,3-Dihydro-1-benzofuran-5-yl)boronic acidHCID 2773380—
ProductHCID 66997753HCID 6699775376.7%

Reaction Steps

The title compound (182 mg) was prepared from 4-bromo-2,6-difluoroaniline (200 mg, 0.96 mmol) and 2,3-dihydrobenzofuran-5-ylboronic acid (204 mg, 1.25 mmol) as a white solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.46 (s, 1H), 7.30 (dd, J 1.8, 8.3, 1H), 7.16 (dd, J 2.1, 8.2, 2H), 6.75 (d, J 8.3, 1H), 5.18 (s, 2H), 4.52 (t, J 8.7, 2H), 3.18 (t, J 8.5, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-f21f101741894a7c98afa3d3f950e7e6
Source noteuspto-grants-2014_04