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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360436Generated: October 30, 2026

(2,3-Dihydro-1-benzofuran-5-yl)boronic acid → HCID 66997690, compound

https://huagongshe.com/reaction/2360436

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2,3-Dihydro-1-benzofuran-5-yl)boronic acidHCID 2773380—
Reactant4-Bromo-2-chloro-6-fluoroanilineHCID 20434620—
ProductHCID 66997690HCID 6699769036.6%

Reaction Steps

The title compound (86 mg) was prepared from 4-bromo-2-chloro-6-fluoroaniline (200 mg, 0.89 mmol) and 2,3-dihydrobenzofuran-5-ylboronic acid (189 mg, 1.16 mmol) as a pale-yellow solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.46 (s, 1H), 7.33-7.25 (m, 3H), 6.75 (d, J 8.3, 1H), 5.36 (s, 2H), 4.52 (t, J 8.7, 2H), 3.18 (t, J 8.6, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-bf70f65ccb794981958e54a2403f5260
Source noteuspto-grants-2014_04