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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360438Generated: October 30, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997748, compound

https://huagongshe.com/reaction/2360438

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant(3-Chloro-5-methoxyphenyl)boronic acidHCID 17750234—
ProductHCID 66997748HCID 6699774830.1%

Reaction Steps

The title compound (39 mg) was prepared from 4-bromo-2,6-difluoroaniline (100 mg, 0.48 mmol) and 3-chloro-5-methoxyphenylboronic acid (116 mg, 0.62 mmol) as a pale-yellow solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.36 (dd, J 2.2, 8.1, 2H), 7.25 (s, 1H), 7.12 (s, 1H), 6.91 (t, J 1.9, 1H), 5.43 (s, 2H), 3.81 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-9525b4fde6f344859dfe23886ebdd19a
Source noteuspto-grants-2014_04