HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2,6-difluoroaniline → HCID 66997151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2,6-difluoroaniline | HCID 610191 | — |
| Reactant | 3-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole | HCID 21072607 | — |
| Product | HCID 66997151 | HCID 66997151 | 54.9% |
Reaction Steps
The title compound (68 mg) was prepared from 4-bromo-2,6-difluoroaniline (100 mg, 0.48 mmol) and 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (160 mg, 0.62 mmol) as a white solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 10.71 (s, 1H), 7.67 (s, 1H), 7.33-7.29 (m, 2H), 7.28-7.21 (m, 2H), 7.09 (s, 1H), 5.12 (s, 2H), 2.27 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686048B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-f8dbece762574bd2b98c8b807c975a69 |
| Source note | uspto-grants-2014_04 |