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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360446Generated: November 1, 2026

4-Bromo-2,6-difluoroaniline → HCID 66997151, compound

https://huagongshe.com/reaction/2360446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,6-difluoroanilineHCID 610191—
Reactant3-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indoleHCID 21072607—
ProductHCID 66997151HCID 6699715154.9%

Reaction Steps

The title compound (68 mg) was prepared from 4-bromo-2,6-difluoroaniline (100 mg, 0.48 mmol) and 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (160 mg, 0.62 mmol) as a white solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 10.71 (s, 1H), 7.67 (s, 1H), 7.33-7.29 (m, 2H), 7.28-7.21 (m, 2H), 7.09 (s, 1H), 5.12 (s, 2H), 2.27 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-f8dbece762574bd2b98c8b807c975a69
Source noteuspto-grants-2014_04