HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2,6-difluoroaniline → 3'-(Ethylthio)-3,5-difluorobiphenyl-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2,6-difluoroaniline | HCID 610191 | — |
| Reactant | [3-(Ethylthio)phenyl]boronic acid | HCID 3484915 | — |
| Product | 3'-(Ethylthio)-3,5-difluorobiphenyl-4-amine | HCID 66996832 | 70.7% |
Reaction Steps
The title compound (900 mg) was prepared from 4-bromo-2,6-difluoroaniline (1 g, 4.8 mmol) and 3-(ethylthio)phenylboronic acid (1.13 g, 6.24 mmol) as a colourless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686048B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-0ace4475fbde40139f1acea75af03bb1 |
| Source note | uspto-grants-2014_04 |