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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360456Generated: October 27, 2026

4-Bromo-2-fluoroaniline → 3-Fluoro-3'-propoxybiphenyl-4-amine

https://huagongshe.com/reaction/2360456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-fluoroanilineHCID 123050—
Reactant(3-Propoxyphenyl)boronic acidHCID 3691230—
Product3-Fluoro-3'-propoxybiphenyl-4-amineHCID 6699720971.3%

Reaction Steps

The title compound (280 mg) was prepared from 4-bromo-2-fluoroaniline (390 mg, 1.6 mmol) and 3-propoxyphenylboronic acid (369 mg, 2 mmol) as a colourless liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-68a0483cb3f3466bb491d27ca4bf94e9
Source noteuspto-grants-2014_04