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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360458Generated: October 25, 2026

4-Bromo-3-fluoroaniline → 3'-(Ethylthio)-2-fluorobiphenyl-4-amine

https://huagongshe.com/reaction/2360458

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-3-fluoroanilineHCID 821848—
Reactant[3-(Ethylthio)phenyl]boronic acidHCID 3484915—
Product3'-(Ethylthio)-2-fluorobiphenyl-4-amineHCID 66997624108.7%

Reaction Steps

The title compound (430 mg) was prepared from 4-bromo-3-fluoroaniline (300 mg, 1.6 mmol) and 3-(ethylthio)phenylboronic acid (370 mg, 2.0 mmol) as a yellow liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686048B2
Source datasetuspto-grants-2014_04
ORD IDord-95b66ac82b58474db103f4aeabc7cc43
Source noteuspto-grants-2014_04