4-Bromoaniline → 1204-42-8

HRID 2360461Notes

Reaction equation

Br[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1B(O)O>>[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 78074-Bromoaniline

HCID 27343222-Chlorophenylboronic acid

Product 1

HCID 41273511204-42-8Yield 49.7%

Procedure

The title compound (176 mg) was prepared from 4-bromoaniline (300 mg, 1.74 mmol) and 2-chlorophenylboronic acid (354 mg, 2.26 mmol) as a yellow solid.

Sources & evidence

ORD record: ord-78a42e7ed24f4987af59a7be6fe8d315
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08686048B2

Reaction notes

Loading…