4-Bromoaniline → HCID 62918566, compound

HRID 2360463Notes

Reaction equation

HRID 2360463 reaction equation
Br[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[F:9][C:10]([F:22])([F:21])[O:11][C:12]1[CH:13]=[C:14](B(O)O)[CH:15]=[CH:16][CH:17]=1>>[F:9][C:10]([F:21])([F:22])[O:11][C:12]1[CH:17]=[C:16]([C:2]2[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=2)[CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 78074-BromoanilineHCID 27343853-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 62918566HCID 62918566, compoundYield 63.5%

Procedure

The title compound (280 mg) was prepared from 4-bromoaniline (300 mg, 1.74 mmol) and 3-(trifluoromethoxy)phenylboronic acid (466 mg, 2.26 mmol) as a pale-yellow liquid.

Sources & evidence

ORD record
ord-e31a73950cef429e8ca903ae0cb06488
Source dataset
uspto-grants-2014_04
Patent number
US08686048B2

Reaction notes

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