4-Bromo-2,3,5,6-tetrafluoroaniline → HCID 86659037, compound

HRID 2360466Notes

Reaction equation

HRID 2360466 reaction equation
Br[C:2]1[C:8]([F:9])=[C:7]([F:10])[C:5]([NH2:6])=[C:4]([F:11])[C:3]=1[F:12].[CH2:13]([O:17][C:18]1[CH:19]=[C:20](B(O)O)[CH:21]=[CH:22][CH:23]=1)[CH2:14][CH2:15][CH3:16]>>[CH2:13]([O:17][C:18]1[CH:23]=[C:22]([C:2]2[C:8]([F:9])=[C:7]([F:10])[C:5]([NH2:6])=[C:4]([F:11])[C:3]=2[F:12])[CH:21]=[CH:20][CH:19]=1)[CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 6186714-Bromo-2,3,5,6-tetrafluoroanilineHCID 50841013-Butoxyphenylboronic Acid

Product 1

HCID 86659037HCID 86659037, compoundYield 64.9%

Procedure

The title compound (250 mg) was prepared from 4-bromo-2,3,5,6-tetrafluoroaniline (300 mg, 1.23 mmol) and 3-butoxyphenylboronic acid (310 mg, 1.59 mmol) as a yellow liquid.

Sources & evidence

ORD record
ord-26c509cb8a1c4c8cac138a7ef4c1bc37
Source dataset
uspto-grants-2014_04
Patent number
US08686048B2

Reaction notes

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