4-Bromoaniline → HCID 66997669, compound

HRID 2360473Notes

Reaction equation

HRID 2360473 reaction equation
Br[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:11]=1B(O)O>>[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:11]=1[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 78074-BromoanilineHCID 17750233(2-Chloro-5-methoxyphenyl)boronic acid

Product 1

HCID 66997669HCID 66997669, compoundYield 75.7%

Procedure

The title compound (154 mg) was prepared from 4-bromoaniline (150 mg, 0.87 mmol) and 2-chloro-5-methoxyphenyl boronic acid (211 mg, 1.13 mmol) as a colourless viscous liquid.

Sources & evidence

ORD record
ord-013ea3e8418d4b3f8cac9e9766171e7c
Source dataset
uspto-grants-2014_04
Patent number
US08686048B2

Reaction notes

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