HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoamyl Nitrite → 5-Tert-butyl-2-methoxy-1-methylsulphanyl-3-nitro-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoamyl Nitrite | HCID 8053 | — |
| Reactant | Dimethyl Disulfide | HCID 12232 | — |
| Reactant | 5-(tert-Butyl)-2-methoxy-3-nitroaniline | HCID 11206863 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 5-Tert-butyl-2-methoxy-1-methylsulphanyl-3-nitro-benzene | HCID 58493929 | — |
Reaction Steps
2 g 5-tert-butyl-2-methoxy-3-nitro-phenylamine are dissolved in 20 ml acetonitrile, combined successively with 3.6 ml isopentylnitrite as well as 2.4 ml dimethyldisulphide and refluxed for 2 h. The solvents are eliminated in vacuo and the residue is chromatographed on silica gel (petroleum ether/ethyl acetate 90:10).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686022B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-26183b1c99964a2bbba39c3fccd96cb7 |
| Source note | uspto-grants-2014_04 |