Pyruvic Acid → HCID 178438025, compound

Participants

Reaction Steps

A mixture of 5-ethyl-2H-pyrazol-3-ylamine (1 g, 9 mmol), 3-fluoro-4-hydroxybenzaldehyde (1.26 g, 9 mmol), pyruvic acid (0.63 ml, 9 mmol) and glacial acetic acid (14 ml) was heated to reflux under nitrogen for 2 h and then cooled to room temperature. The precipitate was filtered and washed with absolute ethanol to afford the title compound (0.614 g, 23%) as beige solid.

Provenance & Evidence