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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360717Generated: November 1, 2026

Acetone Cyanohydrin → 1-Benzyl-5,5-diethyl-2,2-dimethyl-piperazine

https://huagongshe.com/reaction/2360717

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetone CyanohydrinHCID 6406—
ReactantDiethylethylene diamineHCID 432996—
ReactantHCID 64842474HCID 64842474—
Product1-Benzyl-5,5-diethyl-2,2-dimethyl-piperazineHCID 64860648—

Reaction Steps

1-Benzyl-5,5-diethyl-2,2-dimethyl-piperazine was synthesized in analogy to 6-benzyl-8,8-dimethyl-6,9-diaza-spiro[4.5]decane starting from 3-(aminomethyl)pentane-3-amine and acetone cyanohydrin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686150B2
Source datasetuspto-grants-2014_04
ORD IDord-3272d54eb80d47efa253f6baa4ebd1e5
Source noteuspto-grants-2014_04