HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 10-Bromo-5,6-dihydro-benzo[f]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 8-Bromo-1,2,3,4-tetrahydronaphthalen-2-one | HCID 4136187 | — |
| Product | 10-Bromo-5,6-dihydro-benzo[f]quinoline | HCID 58294583 | 49% |
Reaction Steps
The title compound is prepared from 8-bromo-2-tetralone and propargylamine following a procedure analogous to that described in Step 1 of Intermediates 1 and 2. Yield: 49% of theory; LC (method 1): tR=2.68 min; Mass spectrum (ESI+): m/z=260/262 (Br) [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686149B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-c6d6cfd281f1438a9afe7d94172099b8 |
| Source note | uspto-grants-2014_04 |