HCID 58294447, compound → HCID 178474019, compound

HRID 2360942Notes

Reaction equation

HRID 2360942 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[NH:13]1[CH2:18][CH2:17][CH2:16][C@@H:15]2[C:19]3[CH:20]=[CH:21][C:22]([NH:26][C:27](=[O:29])[CH3:28])=[CH:23][C:24]=3[CH2:25][C@H:14]12>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:13]3[CH2:18][CH2:17][CH2:16][C@@H:15]4[C:19]5[CH:20]=[CH:21][C:22]([NH:26][C:27](=[O:29])[CH3:28])=[CH:23][C:24]=5[CH2:25][C@H:14]34)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 58294447HCID 58294447, compoundHCID 178524171HCID 178524171, compound

Product 1

HCID 178474019HCID 178474019, compoundYield 34%

Procedure

The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and N-(cis-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridin-7-yl)-acetamide following a procedure analogous to that described in Example 1. Yield: 34% of theory; LC (method 1): tR=1.97 min; Mass spectrum (ESI+): m/z=375 [M+H]+.

Sources & evidence

ORD record
ord-bddb97ce6dfb4fdea0f0b7a962509588
Source dataset
uspto-grants-2014_04
Patent number
US08686149B2

Reaction notes

Loading…