HCID 67223124, compound → HCID 178486420, compound
Reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:13][O:14][C:15]1[C:16]([CH3:28])=[CH:17][C:18]2[CH2:19][C@H:20]3[C@@H:25]([C:26]=2[CH:27]=1)[CH2:24][CH2:23][CH2:22][NH:21]3>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([N:21]3[CH2:22][CH2:23][CH2:24][C@@H:25]4[C:26]5[CH:27]=[C:15]([O:14][CH3:13])[C:16]([CH3:28])=[CH:17][C:18]=5[CH2:19][C@H:20]34)=[O:12])=[CH:9][C:4]=2[N:3]=[CH:2]1Participants
3
Procedure
The title compound is prepared from 1H-benzoimidazole-5-carboxylic acid and cis-6-methoxy-7-methyl-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine following a procedure analogous to that described in Example 1. LC (method 7): tR=1.04 min; Mass spectrum (ESI+): m/z=362 [M+H]+.
Sources & evidence
- ORD record
- ord-215c49d8033d4d2ba68cf59171cffe41
- Source dataset
- uspto-grants-2014_04
- Patent number
- US08686149B2
Reaction notes
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